A Rapid Experimental Polar Surface Area (EPSA) Assay

Explore EPSA: Transform drug research with a precise, cost-effective assay. Gain deeper insights into molecular polarity and bioavailability.

Understanding Drug Bioavailability with Polar Surface Area

Polar surface area, often synonymous with hydrogen bond availability, stands as a pivotal physical property in comprehending drug bioavailability. Traditionally, a molecule's Topological Polar Surface Area (TPSA) serves as a proxy for this property, aiding in the ranking of similar molecules. However, TPSA sometimes falls short in distinguishing compounds undergoing conformational changes in solution.

 

A Rapid Experimental Polar Surface Area (EPSA) Assay

Explore EPSA: Transform drug research with a precise, cost-effective assay. Gain deeper insights into molecular polarity and bioavailability.